Article

IRF4 haploinsufficiency in a family with Whipple’s disease

2017-10-03

Abstract excerpt

The pathogenesis of Whipple’s disease (WD) remains largely unknown, as WD strikes only a very small minority of the individuals infected with Tropheryma whipplei (Tw). Asymptomatic carriage of Tw is less rare. We studied a large multiplex French kindred, containing four otherwise healthy WD patients (mean age: 76.7 years) and five healthy carriers of Tw (mean age: 55 years). We used a strategy combining genome-wi...

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Literature Corpus work: bfc9ef4c-8a4f-5e84-9b57-3f785e511767
DOI: 10.1101/197145

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