Article

Detection of Emerging Ibrutinib Resistance by Flow Cytometry in Patients with Chronic Lymphocytic Leukemia

2021-12-23

Abstract excerpt

<title>Abstract</title> <p><italic>Purpose:</italic> Bruton’s tyrosine kinase inhibitor ibrutinib has revolutionized the treatment of chronic lymphocytic leukemia (CLL). Although ibrutinib is a highly effective drug, during the treatment acquired ibrutinib resistance may occur and its early detection is an important issue. Our aim was to investigate several phenotypic markers on CLL cells to reveal changes in the...

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Literature Corpus work: bf5cf0ef-4f66-5042-8d8c-39c76aad60a9
DOI: 10.21203/rs.3.rs-1046046/v2

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