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Clinical Phenotyping of Polymyxin-Associated Nephrotoxicity and Phenotype-Specific Prognostic Utility of Neutrophil-to-Platelet Ratio in Carbapenem-Resistant Acinetobacter baumannii Infections

2025-12-01

Abstract excerpt

<title>Abstract</title> <p>Background Carbapenem-resistant Acinetobacter baumannii (CRAB) infections remain therapeutically challenging, often necessitating last-line polymyxin therapy despite substantial nephrotoxicity. Conventional risk assessments for polymyxin-associated acute kidney injury (AKI) frequently overlook patient heterogeneity. We sought to delineate clinical phenotypes of polymyxin-associated AKI...

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Literature Corpus work
bec9dde0-6496-5abc-be51-c3fef7f74a18
DOI
10.21203/rs.3.rs-8146364/v1
Open publication

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Clinical Phenotyping of Polymyxin-Associated Nephrotoxicity and Phenotype-Specific Prognostic Utility of Neutrophil-to-Platelet Ratio in Carbapenem-Resistant Acinetobacter baumannii InfectionsDOI 10.21203/rs.3.rs-8146364/v1
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