Article

ReCellTy: Domain-specific knowledge graph retrieval-augmented LLMs workflow for single-cell annotation

2025-04-26

Abstract excerpt

To enable precise and fully automated cell type annotation with large language models (LLMs), we developed a graph-structured feature–marker database to retrieve entities linked to differential genes for cell reconstruction. We further designed a multi-task workflow to optimize the annotation process. Compared to general-purpose LLMs, our method improves human evaluation scores by up to 0.21 and semantic similarit...

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Literature Corpus work: beba78fb-7dab-5285-b565-b3f013a5142b
DOI: 10.1101/2025.04.23.650201

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