Article

Principal Component Analysis of RNA-seq Data Unveils a Novel Prostate Cancer-Associated Gene Expression Signature

2021-02-09

Abstract excerpt

Prostate cancer (Pca) is a highly heterogeneous disease and the second more common tumor in males. Molecular and genetic profiles have been used to identify subtypes and guide therapeutic intervention. However, roughly 26% of primary Pca are driven by unknown molecular lesions. We use Principal Component Analysis (PCA) and custom RNAseq-data normalization to identify a gene expression signature which segregates pr...

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Literature Corpus work: be6ab516-90bb-51ab-9d5b-d76e8ae6865e
DOI: 10.20944/preprints202102.0234.v1

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