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UGT1A1 polymorphism has a prognostic effect in patients with stage IB or II uterine cervical cancer and one or no metastatic pelvic nodes receiving irinotecan chemotherapy

2020-07-29

Abstract excerpt

<title>Abstract</title> <p>Background : Uridine diphosphate glucuronosyltransferase 1 family polypeptide A1 (UGT1A1 ) is a predictive biomarker for the side-effects of irinotecan; irinotecan chemotherapy reduces the volume of tumors harboring UGT1A1 polymorphisms. We aimed to determine whether UGT1A1 polymorphisms can predict progression-free survival in patients with local cervical cancer treated with irinotecan...

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Literature Corpus work
bdf8ac71-765a-5e28-a37b-ddce90ed3dd4
DOI
10.21203/rs.3.rs-27689/v3
Open publication

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