Article

Unraveling the Core: Hub Genes Bridging Familial and Sporadic Parkinson’s Disease

2024-02-21

Abstract excerpt

Parkinson’s disease (PD), a neurodegenerative disorder characterized by dopaminergic (DA) neuron loss in the substantia nigra, manifests as familial (genetically linked) or idiopathic (sporadic) forms. Despite distinct etiologies, both subtypes converge on shared pathological mechanisms that remain poorly understood. This study focused on identifying “hub genes” that might drive DA neuron degeneration in familial...

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Literature Corpus work: bdf28576-ed97-5292-8a16-006c41605a0c
DOI: 10.1101/2024.02.19.580936

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