Article

Identification of metabolic pathways and key genes associated with Atypical Parkinsonism using a systems biology approach

2023-07-06

Abstract excerpt

<title>Abstract</title> <p>Atypical parkinsonism (AP) is a group of complex neurodegenerative disorders with marked clinical and pathophysiological heterogeneity. The use of systems biology tools may contribute to the characterization of hub-bottleneck genes, and the identification of its metabolic pathways to broaden the understanding of the bases of these disorders. A systematic search was performed on the DisG...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 4a8d8283-045b-5b88-9032-29b881019796
DOI: 10.21203/rs.3.rs-3015470/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Identification of metabolic pathways and key genes associated with Atypical Parkinsonism using a systems biology approachDOI 10.21203/rs.3.rs-3015470/v1Read

Genetic networks in Parkinson’s and Alzheimer’s diseaseSemantic proximity Read

Identification of Potential Core Genes in Parkinson’s Disease Using Bioinformatics AnalysisSemantic proximity Read

Bioinformatics and next generation sequencing data analysis to identify key genes and pathways influencing in Parkinson’s diseaseSemantic proximity Read

A comparative system-level analysis of the neurodegenerative diseases.Semantic proximity Read

Novel susceptibility genes and molecular mechanisms identified in relation to mitochondrial dysfunctions in Parkinson’s diseaseSemantic proximity Read

Towards a pathway definition of Parkinson’s disease: a complex disorder with links to cancer, diabetes and inflammationSemantic proximity Read

Uncovering systems-level molecular similarities between Alzheimer’s and Parkinson’s diseasesSemantic proximity Read

Identification and Validation of Oxidative Stress-Related Hub Genes in Parkinson’s DiseaseSemantic proximity Read

Neurodegenerative disorders: From clinicopathology convergence to systems biology divergence.Semantic proximity Read

Reconstruction of gene network associated with Parkinson disease for gene targets searchSemantic proximity Read

Pathway analysis of genome-wide association studies for Parkinson's disease.Semantic proximity Read

Exploring the hub genes and potential mechanisms of complement system-related genes in Parkinson disease: based on transcriptome sequencing and Mendelian randomizationSemantic proximity Read