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HDL-Triglyceride Index: A Kinetically-Derived Biomarker for Time-Integrated Triglyceride Exposure and Cardiometabolic Risk

2025-10-18

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> High-density lipoprotein (HDL) particles undergo dynamic remodeling through triglyceride (Tg) enrichment via cholesteryl ester transfer protein-mediated exchange, yet clinical assessment tools capturing this temporal integration remain lacking. Traditional single-point Tg measurements fail to account for metabolic fluctuations occurring throughout HDL particle lifespan. <h4>...

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Literature Corpus work
bd966ef6-9f76-549c-8b6d-38707399325e
DOI
10.1101/2025.10.18.683254
Open publication

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HDL-Triglyceride Index: A Kinetically-Derived Biomarker for Time-Integrated Triglyceride Exposure and Cardiometabolic RiskDOI 10.1101/2025.10.18.683254
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