Article

Deep brain stimulation for major depressive disorder: A Systematic Review and Meta-Analysis

2025-08-27

Abstract excerpt

<title>Abstract</title> <p>A significant proportion of patients with major depressive disorder (MDD) experience treatment-resistant depression (TRD). Deep brain stimulation (DBS) is a surgical intervention under investigation for TRD which has shown promise in some settings but inconsistent outcomes overall. We conducted a random-effects meta-analysis of open-label and randomized controlled trials to provide an u...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: bd3f5339-c479-5f4d-8487-2e90f92e184a
DOI: 10.21203/rs.3.rs-7238063/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Deep brain stimulation for major depressive disorder: A Systematic Review and Meta-AnalysisDOI 10.21203/rs.3.rs-7238063/v1Read

Low Intensity Ultrasound Neuromodulation for the treatment of Major Depressive Disorder: Systematic Review and Meta‑Analysis of Randomized Controlled TrialsSemantic proximity Read

Randomized trial, parallel-group to compare effect of low-intensity transcranial magnetic stimulation (Li-TMS) on sleep disorders, inflammation levels, and brain-derived neurotrophic factor in patients with depressionSemantic proximity Read

Use of deep brain stimulation in treatment-resistant depressionSemantic proximity Read

Transcranial random noise stimulation for the acute treatment of depression: a randomized controlled trialSemantic proximity Read

A new translational target for deep brain stimulation to treat depression.Semantic proximity Read

Multichannel tDCS with Advanced Targeting for Major Depressive Disorder: A Tele-Supervised At-Home Pilot StudySemantic proximity Read

Non-invasive brain stimulation effectiveness in anxiety disorder treatment: a meta-analysis on sham/behavior-controlled studiesSemantic proximity Read

Real-world effectiveness of a single-day regimen for transcranial magnetic stimulation using Optimized, Neuroplastogen-Enhanced techniques in Depression (ONE-D)Semantic proximity Read

Acute and long-term effects of repetitive transcranial magnetic stimulation in major depressive episodes: a systematic review and dose-response meta-analysis of randomized sham-controlled trialsSemantic proximity Read

Single-day accelerated TMS with D-cycloserine augmentation for depression: A placebo-controlled trialSemantic proximity Read

Effect of Non-invasive Spinal Cord Stimulation in Unmedicated Adults with Major Depressive Disorder: A Pilot Randomized Controlled Trial and Induced Current Flow PatternSemantic proximity Read

Application of Neuromodulation Techniques in Anxiety Treatment: A Systematic ReviewSemantic proximity Read