Article

Gut microbiota-dependent increase in phenylacetic acid induces endothelial cell senescence during aging

2023-11-17

Abstract excerpt

Endothelial cell (EC) senescence plays a crucial role in the development of cardiovascular diseases in aging population. Gut microbiota alterations are emerging as significant factors present in cellular senescence associated with aging. However, little is known about how aging-related changes in gut microbiota are causally implicated in EC senescence. Here we show that gut microbiota-dependent phenylacetic acid (...

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Literature Corpus work: bcf812b5-d006-52c9-8e4d-dd3f560a63f6
DOI: 10.1101/2023.11.17.567594

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