Computational Screening of Secretory Proteins With Brain-Specific Expression in Glioblastoma Multiforme

Abstract excerpt

<title>Abstract</title> <p>Glioblastoma multiforme (GBM) is a widely spread and fatal primary brain tumor with an increased risk of relapse in spite of aggressive treatment. The current procedures for GBM diagnosis include invasive procedures i.e. resection or biopsy to acquire tumor mass. Implementation of negligibly invasive tests as potential diagnostic technique and biofluid-based monitoring of GBM emphases o...

Topics

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• Cancer Mechanisms and Therapy
• Ferroptosis and cancer prognosis
• Glioma Diagnosis and Treatment
• Iron Metabolism and Disorders
• Meningioma and schwannoma management
• Peptidase Inhibition and Analysis
• Protease and Inhibitor Mechanisms
• Single-cell and spatial transcriptomics

Identifiers and source

Literature Corpus work

bce53df8-01ec-52a1-a22b-e5970f6235dd

DOI

10.21203/rs.3.rs-930442/v1