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LYCEUM: Learning to call copy number variants on low coverage ancient genomes

2024-10-29

Abstract excerpt

Copy number variants (CNVs) are pivotal in driving phenotypic variation that facilitates species adaptation. They are significant contributors to various disorders, making ancient genomes crucial for uncovering the genetic origins of disease susceptibility across populations. However, detecting CNVs in ancient DNA (aDNA) samples poses substantial challenges due to several factors: (i) aDNA is often highly degraded...

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Literature Corpus work: bc3448a4-b421-5752-a0e6-38deefe6fe75
DOI: 10.1101/2024.10.28.620589

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