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The Regional Landscape of the Human Colon Culturome in Health and Cystic Fibrosis

2025-09-29

Abstract excerpt

Cystic fibrosis (CF) alters gut physiology, yet its impact on microbial communities across colonic regions (ascending, transverse, descending colon) and microhabitats (lumen, mucosa) remains incompletely understood. Here, we applied culturomics to characterize gut microbiota in 32 individuals (22 nonCF, 10 CF). Persons with CF (pwCF) exhibited significantly higher viable bacterial loads than nonCF individuals, par...

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Literature Corpus work
bc2b797a-9e2b-59c3-bef5-c55d42cb0b2b
DOI
10.1101/2025.09.29.679198
Open publication

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The Regional Landscape of the Human Colon Culturome in Health and Cystic FibrosisDOI 10.1101/2025.09.29.679198
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