Article

Transcriptome Alterations in Myotonic Dystrophy Frontal Cortex

2020-09-09

Abstract excerpt

Myotonic dystrophy (dystrophia myotonica, DM) is caused by expanded CTG/CCTG microsatellite repeats, leading to multi-systemic symptoms in skeletal muscle, heart, gastrointestinal, endocrine, and central nervous systems (CNS), among others. For some patients, CNS issues can be as debilitating or more so than muscle symptoms; they include hypersomnolence, executive dysfunction, white matter atrophy, and neurofibril...

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Literature Corpus work: bc1bdd7c-fa25-5554-847f-cbe411610920
DOI: 10.1101/2020.09.09.284505

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