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SKP alleviates the ferroptosis in diabetic kidney disease through suppression of HIF-1α/HO-1 pathway based on network pharmacology analysis and experimental validation.

2024-01-09

Abstract excerpt

<title>Abstract</title> <p><bold>Backgroud</bold> Diabetic kidney disease (DKD) represents a microvascular complication of diabetes mellitus. Shenkang Pills (SKP), a traditional Chinese medicine formula, has been widely used in the treatment of DKD and has obvious antioxidant effect. Ferroptosis, a novel mode of cell death due to iron overload, has been shown to be associated with DKD. Nevertheless, the precise e...

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Literature Corpus work
bb447566-4b05-51e0-8679-9e0bcc48509a
DOI
10.21203/rs.3.rs-3799288/v1
Open publication

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SKP alleviates the ferroptosis in diabetic kidney disease through suppression of HIF-1α/HO-1 pathway based on network pharmacology analysis and experimental validation.DOI 10.21203/rs.3.rs-3799288/v1
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