Article

Uncovering the Pathophysiological Pattern of Expression from Integrated Analysis across Uniformly Processed RNA Sequencing COVID-19 Datasets

2025-06-20

Abstract excerpt

<h4>Background</h4> Post-acute sequelae of SARS-CoV-2 infection (PASC) affects millions globally, yet the molecular mechanisms underlying acute COVID-19 and its chronic sequelae remain poorly understood. <h4>Methods</h4> We performed an integrative transcriptomic analysis of three independent RNA-seq datasets, capturing the complete COVID-19 pathophysiology from health through acute severe infection to post-acut...

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Literature Corpus work: bb1b594e-b158-52d5-b27d-7411eaf9077c
DOI: 10.1101/2025.06.18.660454

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