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Integration of transcriptomics, proteomics, phosphoproteomics analysis for characterization of pulmonary arterial hypertension in Chinese people

2024-02-09

Abstract excerpt

<h4>Background: </h4> Pulmonary arterial hypertension (PAH), a fatal disease, is characterized by pulmonary vascular remodeling and vascular resistance. However, the molecular mechanisms underlying the pathogenesis of PAH remained to be incompletely understood. Methods RNA-seq, 4D Lable-free proteomics and phosphoproteomics were used to detect the levels of mRNA, proteins, and phosphoproteins in lung tissues from...

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Literature Corpus work
bacbbd71-5fdd-51e5-9005-b5f817cc271f
DOI
10.21203/rs.3.rs-3929686/v1
Open publication

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