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Mortality among patients with invasive group A streptococcal infections caused by the M1<sub>UK</sub>lineage: a retrospective cohort study in England and Wales

2025-06-27

Abstract excerpt

<h4>Background</h4> The M1 UK sublineage of S. pyogenes has dominated post-pandemic upsurges in invasive group A streptococcal (iGAS) disease. Using a national cohort of patients with emm 1 iGAS infections, we compared the case fatality rate (CFR) attributable to M1 UK with ancestral emm 1 lineages. <h4>Methods</h4> We linked emm 1 S. pyogenes iGAS cases in England and Wales between December 2009-July 2022 to demo...

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Literature Corpus work
ba841b9d-f918-54e3-9dbc-404d1d96012a
DOI
10.1101/2025.06.25.25330084
Open publication

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Mortality among patients with invasive group A streptococcal infections caused by the M1<sub>UK</sub>lineage: a retrospective cohort study in England and WalesDOI 10.1101/2025.06.25.25330084
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