Article

The Diagnostic Utility of Prenatal Microarray in High-Risk Pregnancies: A Single-Center Experience to Enhance Reproductive Care and Risk Stratification

2025-07-18

Abstract excerpt

<h4>Background: </h4> /Objective: Prenatal cytogenetic testing is essential for pregnancies at high risk of chromosomal abnormalities. While conventional karyotyping detects large aneuploidies and structural rearrangements (>5–10 Mb), chromosomal microarray analysis (CMA) identifies smaller copy number variants (CNVs), increasing diagnostic yield by approximately 5%. CMA is now recommended as the first-tier tes...

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Literature Corpus work: ba66e9d6-1638-51d0-bbf4-b72f1fcca5a8
DOI: 10.20944/preprints202507.1491.v1

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