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Pilot Evaluation of ddPCR-Based NIPT for Fetal Trisomy Screening in Advanced Maternal Age Pregnancies in Mongolia

2026-06-12

Abstract excerpt

<h4>Background: </h4> /Objectives: Advanced maternal age (≥35 years) significantly increases the risk of fetal chromosomal abnormalities, particularly trisomies 21, 18, and 13. Non-invasive prenatal testing (NIPT) based on cell-free fetal DNA (cffDNA) in maternal plasma has substantially improved the accuracy and safety of prenatal screening. <h4>Methods:</h4> We previously developed and clinically validated a mul...

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Literature Corpus work
ba486622-ba43-51c9-b6d6-e86c2c7628b4
DOI
10.20944/preprints202606.0972.v1
Open publication

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Pilot Evaluation of ddPCR-Based NIPT for Fetal Trisomy Screening in Advanced Maternal Age Pregnancies in MongoliaDOI 10.20944/preprints202606.0972.v1
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