Article

Validation criteria for genetic animal models of epilepsy

2010-01-01

Abstract excerpt

In the past decades, several mutant genes that encode ion channel subunit proteins or their functionally-related proteins have been identified in pedigrees of idiopathic epilepsy. To explore the pathogenesis and pathophysiology of epilepsy syndrome, the functional abnormalities of transmission in genetic animal models bearing the mutant genes identified in pedigrees of idiopathic epilepsy should be analyzed. In sp...

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Literature Corpus work: ba45cc1e-c364-58bb-8c6d-f759336dfd64
DOI: 10.3805/eands.3.109

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