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Integrated Analysis of the Anoikis‐Related Signature Identifies Rac Family Small GTPase 3 as a Novel Tumor‐Promoter Gene in Hepatocellular Carcinoma

22 Mar 2025

Abstract excerpt

Anoikis resistance in hepatocellular carcinoma (HCC) cells boosts survival and metastasis. This study aimed to establish an anoikis-related genes (ARGs)-based model for predicting HCC patients' outcomes and investigate the clinicopathological significance and function of crucial ARGs. The transcriptional expression patterns for HCC cohorts were compiled from TCGA, GEO and ICGC. Univariate and LASSO multivariate...

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PMID: 40123831
DOI: 10.1002/mco2.70125

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