Article

Deep learning enables feature extraction of 3D collagen architecture in cleared fibrotic tissues

2026-02-26

Abstract excerpt

<h4>ABSTRACT</h4> Light-sheet fluorescence microscopy enables deep optical sectioning of large, cleared biological tissues. However, effective clearing of collagen-rich tissues remains a persistent technical challenge. Moreover, standardized workflows integrating three-dimensional imaging with computational analysis of collagen architecture are currently unavailable. Here, we present an integrated pipeline combin...

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Literature Corpus work: b9fb0680-7367-5846-804b-fc6b2a926545
DOI: 10.64898/2026.02.25.707675

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