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Brain dopamine imbalance causes follicle death and underlies negative effect of high sugar diet during <i>Drosophila</i> oogenesis

2025-04-29

Abstract excerpt

<h4>ABSTRACT</h4> Unhealthy diets, obesity, and low fertility are associated in Drosophila and humans. We previously showed that a high sugar diet, but not obesity, reduces Drosophila female fertility owing to increased death of newly formed germline cysts and vitellogenic follicles. Drosophila strains carrying mutations in the yellow ( y ) and white ( w ) pigmentation genes are routinely used for investig...

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Literature Corpus work
b99d45b4-9131-58ed-939d-cb2739259de1
DOI
10.1101/2025.04.25.650701
Open publication

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