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Article

A Cell-Based Assay for Detection of Anti-Fibrillarin Autoantibodies in Systemic Sclerosis

2022-06-09

Abstract excerpt

<h4>Objectives</h4> Anti-fibrillarin antibodies are useful for establishing diagnosis and predicting distinct clinical features in systemic sclerosis (SSc). Anti-fibrillarin produces a characteristic clumpy nucleolar pattern in indirect immunofluorescence assay on HEp-2 cells (HEp-2 IFA) that is useful to guide further testing in antigen-specific immunoassays (ASI). Immunoprecipitation (IP) is the gold standard AS...

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Literature Corpus work
b98a81a7-05b9-571c-b562-7087ba71c3db
DOI
10.1101/2022.06.07.22276113
Open publication

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A Cell-Based Assay for Detection of Anti-Fibrillarin Autoantibodies in Systemic SclerosisDOI 10.1101/2022.06.07.22276113
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