Article

S2F-Agent: Harnessing sequence-to-function models for verifiable genome interpretation

2026-05-15

Abstract excerpt

Sequence-to-function (S2F) models offer a revolutionary paradigm for genotype-phenotype mapping, yet their broader application is bottlenecked by the need for reliable orchestration and interpretation across a fragmented model ecosystem. While general-purpose language models can automate scientific workflows, they are not inherently grounded in the model-specific execution constraints required for robust S2F analy...

Identifiers and source

Literature Corpus work: b9774a15-0f17-51ff-9a59-e7e2f437d9eb
DOI: 10.64898/2026.05.13.724757

Open publication

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Click a neighbor to travelStep 1 · 12 closest

S2F-Agent: Harnessing sequence-to-function models for verifiable genome interpretationDOI 10.64898/2026.05.13.724757Read

BiOmics: A Foundational Agent for Grounded and Autonomous Multi-omics InterpretationSemantic proximity Read

MARRVEL-MCP: An agentic interface for Mendelian disease discovery via tool-augmented context engineering.Semantic proximity Read

ChromSkills enables interpretable and reproducible agentic chromatin data analysisSemantic proximity Read

AIVA: An Agentic Platform for Phenotype-Aware Variant Analysis, Interpretation and Clinical Decision Support in Rare DiseaseSemantic proximity Read

Benchmarking large language models for ACMG/AMP variant interpretation and variant callingSemantic proximity Read

PantheonOS: An Evolvable Multi-Agent Framework for Automatic Genomics DiscoverySemantic proximity Read

MARRVEL-MCP: A Context-Engineered Natural-Language Query-to-Response Interface for Mendelian Disease DiscoverySemantic proximity Read

Pipette: Encoding scientific literature into an executable Skill Graph for multi-agent bioinformaticsSemantic proximity Read

AI in variant analysis: fast track to genetic diagnoses.Semantic proximity Read

MAGI: Mechanistic Consequences of Genetic Variants via Genomic Foundation ModelsSemantic proximity Read

SpatialClaw: A Memory-Augmented Autonomous Ecosystem for Spatial Omics AnalysisSemantic proximity Read

DeepSeq: High-Throughput Single-Cell RNA Sequencing Data Labeling via Web Search-Augmented Agentic Generative AI Foundation ModelsSemantic proximity Read