Article
Genomic characterization of six virus-associated cancers identifies changes in the tumor microenvironment and altered genetic programming
2018-03-27
Abstract excerpt
Viruses affect approximately 20% of all human cancers and express immunogenic proteins that make these tumor types potent targets for immune checkpoint inhibitors. In this study, we apply computational tools to The Cancer Genome Atlas and other datasets to define how virus infection shapes the tumor microenvironment and genetic architecture of 6 virus-associated tumor types. Across cancers, the cellular compositio...
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Identifiers and source
- Literature Corpus work
- b960000b-3694-525e-946c-9ffa286dbd0e
- DOI
- 10.1101/289900