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Heme-Containing Enzymes Generate Hydrogen Peroxide from Molecular Hydrogen: Implications for Redox Signaling in Human Cells

2026-06-16

Abstract excerpt

<title>Abstract</title> <p>Molecular hydrogen (H2) has long been regarded as metabolically inert gas in mammalian organism, lacking any known enzymatic catalysts for its activation. Nevertheless, numerous studies have reported that H2 modulates cellular redox signaling, a paradox not explained by the popular hypothesis of its radical scavenging effect. Here, we demonstrate that H2 promotes hydrogen peroxide (H2O2...

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Literature Corpus work
b94e5993-82d0-5c9e-a429-c1068e4a81a7
DOI
10.21203/rs.3.rs-9985046/v1
Open publication

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Heme-Containing Enzymes Generate Hydrogen Peroxide from Molecular Hydrogen: Implications for Redox Signaling in Human CellsDOI 10.21203/rs.3.rs-9985046/v1
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