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<i>Staphylococcus aureus</i> wall teichoic acid is a pathogen-associated molecular pattern that is recognized by langerin (CD207) on skin Langerhans cells

2017-12-22

Abstract excerpt

Staphylococcus aureus is a major cause of skin and soft tissue infections and aggravator of the inflammatory skin disease atopic dermatitis (AD). Epicutaneous exposure to S. aureus induces Th17 responses through skin Langerhans cells (LCs), which paradoxically contribute to host defense but also to AD pathogenesis. The underlying molecular mechanisms of the association between S. aureus and skin inflammation are...

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Literature Corpus work
b94a00a9-49ab-5b3b-a59b-004d15a1ba89
DOI
10.1101/238469
Open publication

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