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Neurodegenerative Plasma Biomarkers for Prediction of Hippocampal Atrophy in Older Adults with Suspected Alzheimer’s Disease in Kinshasa, Democratic Republic of Congo

2024-09-04

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Objective</h4> The hippocampus is one of the first brain structures affected by Alzheimer’s disease (AD), and its atrophy is a strong indicator of the disease. This study investigates the ability of plasma biomarkers of AD and AD-related dementias— amyloid-β (Aβ42/40), phosphorylated tau-181 (p-tau181), neurofilament light (NfL), and glial fibrillary acidic protein (GFAP)—to predict hippoca...

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Literature Corpus work
b897a101-c31d-577a-8468-f04324ac9740
DOI
10.1101/2024.09.03.24313019
Open publication

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Neurodegenerative Plasma Biomarkers for Prediction of Hippocampal Atrophy in Older Adults with Suspected Alzheimer’s Disease in Kinshasa, Democratic Republic of CongoDOI 10.1101/2024.09.03.24313019
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