Article

Cardio-centric hemodynamic management improves spinal cord oxygenation and mitigates hemorrhage in acute spinal cord injury

2020-03-30

Abstract excerpt

Chronic high-thoracic and cervical spinal cord injury (SCI) results in a complex phenotype of cardiovascular consequences, including impaired left-ventricular contractility. Here, we sought to determine whether such dysfunction manifests immediately post-injury, and if so, whether correcting impaired contractility can improve spinal cord oxygenation (SCO 2 ), blood flow (SCBF) and metabolism. Using a porcine mode...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: b8907e96-e343-5f65-a53f-e71ac5d036e3
DOI: 10.1101/2020.03.29.014498

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Cardio-centric hemodynamic management improves spinal cord oxygenation and mitigates hemorrhage in acute spinal cord injuryDOI 10.1101/2020.03.29.014498Read

Impact of Supplemental Oxygen on Cardiovascular PhysiologySemantic proximity Read

Contemporary Management of Cardiogenic Shock: A Scientific Statement From the American Heart Association.Semantic proximity Read

Cardiopulmonary Interactions in Combined Septic Shock and ARDS: An Integrative Framework for Phenotyping and Hemodynamic Optimization.Semantic proximity Read

Guide to Temporary Mechanical Support in Cardiogenic Shock: Choosing Wisely.Semantic proximity Read

The Impact of Transcutaneous Spinal Cord Stimulation on Autonomic Regulation after Spinal Cord Injury: A randomized crossover trialSemantic proximity Read

Pointless Yoyo-Perfusion Mode in CPR: Potential Solutions!Semantic proximity Read

Effect of venoarterial extracorporeal membrane oxygenation on left ventricular function in cardiogenic shock with aortic stenosis or mitral regurgitation: an experimental study in porcine modelSemantic proximity Read

Mechanical Versus Manual Ventilation During Cardiopulmonary Resuscitation: A Systematic Review and Meta-AnalysisSemantic proximity Read

Effect of Cervical Epidural Stimulation After Neurological Damage: Protocol for Phase I/II Open Label Controlled CE-STAND TrialSemantic proximity Read

Smooth muscle phenotype switching in blast traumatic brain injury-induced cerebral vasospasm.Semantic proximity Read

Unveiling Distinct Neuroimmune Responses in Mouse Models of Cervical Spinal Cord Injury: Hemisection versus HemicontusionSemantic proximity Read

Phenotyping hemodynamic response to veno-arterial extracorporeal membrane oxygenation in cardiogenic shock.Semantic proximity Read