Article

Machine learning-based integration identifies ferroptosis hub genes in nonalcoholic steatohepatitis

2023-09-27

Abstract excerpt

<h4>Background: </h4> Ferroptosis, an iron-dependent mode of cellular demise, precipitates the accumulation of lipid peroxides and perturbation of vital metabolic routes, culminating in hepatic impairment. However, the pivotal genes governing the contribution of ferroptosis to the pathogenesis of nonalcoholic steatohepatitis (NASH) remain elusive, necessitating a thorough and profound investigation. Methods Emplo...

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Literature Corpus work: b86c2088-daa3-59bb-a835-9bc54a693be4
DOI: 10.21203/rs.3.rs-3373283/v1

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