Article

SIRT1 promotes EMT, migration and invasion by regulating mTORC1/4E-BP1 in colorectal cancer

2020-02-24

Abstract excerpt

<title>Abstract</title> <p>Background Metastasis, rather than primary tumors, was accounted for the most cases of cancer death in colorectal cancer(CRC). The understanding of the underlying mechanism associated with tumor metastasis would improve the patient’s miserable fate. SIRT1 has been identified to play a role in tumorigenesis and progression of malignant tumors, especially in keeping the characteristics of...

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Literature Corpus work: b83626bc-3847-5436-ba5a-4bc5795831e9
DOI: 10.21203/rs.2.24358/v1

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