Back to search

Article

Nuclear movement generate binuclear cells during neural transdifferentiation from human bone marrow-derived mesenchymal cells

2022-05-31

Abstract excerpt

Although it has been reported that bone marrow-derived mesenchymal stromal cells (BM-MSCs) can transdifferentiate into neural cells, the findings is considered unlikely. Cytotoxic-induced cell changes and cell fusion events are alternative explanations for these observations in culture and transplantation studies, respectively.Here, we show that BM-MSCs neural transdifferentiation involves a formation of dediffere...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
b8297e54-8cf8-51d5-9997-c84b9d7fa914
DOI
10.21203/rs.3.rs-1707146/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Nuclear movement generate binuclear cells during neural transdifferentiation from human bone marrow-derived mesenchymal cellsDOI 10.21203/rs.3.rs-1707146/v1
Binucleated cells generated by nuclear movement during neural transdifferentiation from human bone marrow-derived mesenchymal cellsSemantic proximity
Binucleated human bone marrow-derived mesenchymal cells can be formed during neural-like differentiation with independence of any cell fusion eventsSemantic proximity
The nuclei of human adult stem cells can move within the cell and generate cellular protrusions to contact other cellsSemantic proximity
Differentiation of human adult-derived stem cells towards a neural lineage involves a de-differentiation event prior to re-differentiation to neural phenotypesSemantic proximity
Differentiation of human adult-derived stem cells towards a neural lineage involves a dedifferentiation event prior to differentiation to neural phenotypesSemantic proximity
Phenotypic characteristics of hybrid cells generated by transferring neuronal nuclei into bone marrow stromal cell cytoplasts.Semantic proximity
Non-proliferative adult neurogenesis in neural crest-derived stem cells isolated from human periodontal ligamentSemantic proximity
Non-proliferative neurogenesis in human periodontal ligament stem cellsSemantic proximity
Mesenchymal stem cells generate distinct functional hybrids in vitro via cell fusion or entosisSemantic proximity
Neuron-Like Differentiation of Bone Marrow-Derived Mesenchymal Stem CellsSemantic proximity
Marrow stromal cells, mitosis, and neuronal differentiation: stem cell and precursor functions.Semantic proximity
Switching from bone marrow‐derived neurons to epithelial cells through dedifferentiation and translineage redifferentiationSemantic proximity
Select a neighboring publication to make it the new centre.