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A Deep Learning-Derived Insulin Resistance Index for Cardiovascular Risk Prediction: A Prospective Cohort Study with External Validation in Chinese and US Populations

2026-08-12

Abstract excerpt

<h4>Background</h4> Existing insulin resistance (IR) indices are predominantly developed in diabetic cohorts, limiting their generalizability. We developed a novel deep neural network–derived IR index (DNN-IR) using a Mixture-of-Experts (MoE) framework and evaluated its predictive performance for incident cardiovascular disease (CVD) and mortality in general populations. <h4>Methods</h4> We utilized data from th...

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Literature Corpus work
b6e7970c-ff0e-597e-a34a-d8b1dd3a9fc1
DOI
10.64898/2026.08.10.26360145
Open publication

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A Deep Learning-Derived Insulin Resistance Index for Cardiovascular Risk Prediction: A Prospective Cohort Study with External Validation in Chinese and US PopulationsDOI 10.64898/2026.08.10.26360145
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