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Macrophages prime KRT14+ ductal progenitor cells to drive regeneration in the salivary gland following radiation-induced injury

2026-08-25

Abstract excerpt

<title>Abstract</title> <p>The salivary glands often become damaged in individuals receiving radiotherapy for head and neck cancer, resulting in chronic dry mouth. This has a detrimental effect on patient health and quality of life, for which there is no cure. Regeneration of the injured tissue holds therapeutic promise. Keratin-14 positive (KRT14+) epithelial progenitor cells are responsible for the replenishmen...

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Literature Corpus work
b66778f7-0e94-5395-92ec-1afc6a042ee8
DOI
10.21203/rs.3.rs-10703536/v1
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Macrophages prime KRT14+ ductal progenitor cells to drive regeneration in the salivary gland following radiation-induced injuryDOI 10.21203/rs.3.rs-10703536/v1
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