Article

The Mechanism of Talaromyces Marneffei Influencing Macrophage RAW264.7 Polarization and Sterilization Ability via Arginine Metabolism Pathway

2020-09-03

Abstract excerpt

<title>Abstract</title> <p>Background The opportunistic fungi <italic>T. marneffei</italic> is an intracellular pathogen that causes systemic and lethal infection through the mononuclear phagocyte system. Macrophages act as pacesetters to resist pathogen invasion and communicators to activate adaptive immunity. During infection, macrophages induce iNOS to generate NO, which kills invading pathogenic microorganis...

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Literature Corpus work: b5f44aa4-8d18-5c3e-8bf1-c9144dda684a
DOI: 10.21203/rs.3.rs-48911/v1

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