Article

Integration of mechanical testing, <i>in vivo</i> optical coherence elastography and personalized finite element modeling to predict geometrical outcomes of corneal cross-linking

2025-09-06

Abstract excerpt

<h4>Purpose</h4> Corneal cross-linking (CXL) induces both mechanical and geometrical changes in the cornea, which are typically overlooked in pre-operative planning. We propose a patient-specific finite element model (FEM) to predict the topographic alterations resulting from CXL. <h4>Methods</h4> To calibrate the model, we performed nanoindentation and ex vivo OCE inflation tests before and after CXL on five h...

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Literature Corpus work: b4198427-11e5-58e8-85f9-9a21f1dbeb03
DOI: 10.1101/2025.09.02.673622

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