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Identification of Key Genes Governing the Effects of Physical Activity on Ferroptosis in Alzheimer’s Disease Patients: A Machine Learning-Based Study

2025-09-12

Abstract excerpt

Disrupted brain iron metabolism and activated ferroptosis during ageing constitute significant precursors to neurodegenerative diseases. However, whether exercise intervention can modulate ferroptosis-related genes in the central nervous system remains unsystematically elucidated. This study integrated an aged cohort transcriptome dataset (GSE110298) from the GEO database (comprising 11 low-exercise and 23 high-ex...

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Literature Corpus work
b36e56b6-da61-5a9d-a4d1-d1314f005cc0
DOI
10.1101/2025.09.08.25335383
Open publication

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Identification of Key Genes Governing the Effects of Physical Activity on Ferroptosis in Alzheimer’s Disease Patients: A Machine Learning-Based StudyDOI 10.1101/2025.09.08.25335383
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