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Article

Accelerated Hypofractionation for Elderly or Frail Patients with a Newly Diagnosed Glioblastoma Improves Survival

2021-10-25

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold>The standard of care for elderly glioblastoma (GBM) patients is 40 Gy in 15 fraction radiotherapy with temozolomide (TMZ). However, this regimen has a lower biologic equivalent dose (BED) compared to the Stupp regimen of 60 Gy in 30 fractions. We hypothesize that accelerated hypofractionated radiation of 52.5 Gy in 15 fractions (BED equivalent to Stupp) will have...

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Literature Corpus work
b3507926-b41e-5c29-91e0-59bee6523fd6
DOI
10.21203/rs.3.rs-992179/v1
Open publication

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Accelerated Hypofractionation for Elderly or Frail Patients with a Newly Diagnosed Glioblastoma Improves SurvivalDOI 10.21203/rs.3.rs-992179/v1
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