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P. acnes qPCR-based antibiotics resistance assay (ACQUIRE) reveals widespread macrolide resistance in acne patients and can eliminate macrolide misuse in acne treatment

2021-06-25

Abstract excerpt

<h4>Background</h4> Macrolides have been widely used to treat moderate-to-severe acne for more than 50 years. However, prevalent antibiotic resistance of Propionibacterium acnes , along with the absence of clinically available resistance tests, has made macrolide misuse a frequent occurrence, with serious consequences. <h4>Objective</h4> We developed P. acnes qPCR-based antibiotics resistance assay (ACQUIRE) to en...

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Literature Corpus work: b33a1c2a-c871-51c5-9f31-a09a164c8c3a
DOI: 10.1101/2021.06.21.21256023

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