Article

mRNA cap-binding protein eIF4E1 is a novel regulator of <i>Toxoplasma gondii</i> latency

2023-10-09

Abstract excerpt

The protozoan parasite Toxoplasma gondii causes serious opportunistic disease due to its ability to persist in patients as latent tissue cysts. The molecular mechanisms coordinating conversion between proliferative parasites (tachyzoites) and dormant cysts (bradyzoites) are not fully understood. We previously showed that phosphorylation of eIF2α accompanies bradyzoite formation, suggesting that this clinically re...

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Literature Corpus work: b27d1b27-ae06-5cee-83bd-2e54efd60ce7
DOI: 10.1101/2023.10.09.561274

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