Systematic and integrated analysis of tRNA-derived small RNAs reveals novel potential pathogenesis targets of sarcoidosis

Abstract excerpt

<title>Abstract</title> <p> The pathogenesis of sarcoidosis, which involves several systems, is unclear, and its pathological type is non-caseating epithelioid granulomas. tRNA-derived small RNA (tsRNA) is a novel class of short non-coding RNAs with potential regulatory functions. However, whether tsRNA contributes to sarcoidosis pathogenesis remains unclear. Deep sequencing technology was used to identify alter...

Topics

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• Genetic Association Studies
• Genetic Predisposition to Disease
• Hypoxia-Inducible Factor 1, alpha Subunit
• Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
• Lung
• Sarcoidosis and Beryllium Toxicity Research
• Sarcoidosis, Pulmonary
• Vascular Endothelial Growth Factor A

Identifiers and source

Literature Corpus work

b27c809c-f46d-5426-bae5-1e52024e1a48

DOI

10.21203/rs.3.rs-1230171/v2