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Population genomic molecular epidemiological study of macrolide resistant <i>Streptococcus pyogenes</i> in Iceland, 1995-2016: Identification of a large clonal population with a <i>pbp2x</i> mutation conferring reduced <i>in vitro</i> β-lactam susceptibility

2020-05-13

Abstract excerpt

<h4>ABSTRACT</h4> Resistance to macrolide antibiotics is a global concern in the treatment of Streptococcus pyogenes (Group A Streptococcus, GAS) infections. In Iceland, since the detection of the first macrolide-resistant isolate in 1998, three epidemic waves of macrolide-resistant GAS infections have occurred with peaks in 1999, 2004, and 2008. We conducted whole genome sequencing of all 1,575 available GAS ma...

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Literature Corpus work
b1a93bae-e5fd-5200-8b52-fce24b3083b3
DOI
10.1101/2020.05.12.090365
Open publication

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Population genomic molecular epidemiological study of macrolide resistant <i>Streptococcus pyogenes</i> in Iceland, 1995-2016: Identification of a large clonal population with a <i>pbp2x</i> mutation conferring reduced <i>in vitro</i> β-lactam susceptibilityDOI 10.1101/2020.05.12.090365
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