Article

Somatic GJA4 Mutation in Intracranial Extra-axial Cavernous Hemangiomas

2022-11-16

Abstract excerpt

Extra-axial cavernous hemangiomas (ECHs) are sporadic and rare intracranial occupational lesions that usually occur within the cavernous sinus. The etiology of ECHs remains unknown. In this study, whole-exome sequencing was performed on ECH lesions from 12 patients (discovery cohort) and ddPCR was used to confirm the identified mutation in 46 additional cases (validation cohort). Laser capture microdissection (LCM...

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Literature Corpus work: b1865f1c-ace9-57d6-92cd-351df93d7b43
DOI: 10.21203/rs.3.rs-2266184/v1

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