Article

Higher <i>in vitro</i> mucin degradation, but no increased paracellular permeability by faecal water from Crohn’s disease patients

2022-08-26

Abstract excerpt

<h4>Background</h4> Crohn’s disease (CD) is a chronic inflammatory gastro-intestinal condition with variable disease course. Impaired barrier function and microbial dysbiosis are associated with disease onset and exacerbations. We hypothesized that perturbed microbial activity may contribute to the impaired barrier function in CD. Therefore, this study aimed to examine the impact of faecal bacterial products of a...

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Literature Corpus work: b0db6558-4b40-55d0-8264-150798eae3db
DOI: 10.1101/2022.08.26.505386

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