Increased occurrence of migraine aura and susceptibility to spreading depolarizations at altitude

Abstract excerpt

Headache is a common consequence of ascent to high altitudes, and acute mountain sickness shares many features with migraine. Evidence also suggests that the prevalence of migraine is increased in people living at both high and moderate elevations. Here we identify an increased occurrence of migraine aura with increasing elevation. Our findings are supported by multiple lines of clinical evidence including a chart...

Topics

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• Acute Disease
• Altitude
• Altitude Sickness
• Brain Edema
• Chronic Disease
• Genetic Predisposition to Disease
• Hypertension, Pulmonary
• Hypoxia

Identifiers and source

Literature Corpus work

b0bd7ccb-8cdb-5fa7-ab8e-6d0e91cbca36

DOI

10.1101/2025.08.09.25333153