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Integrative Multi-omics Profiling Reveals CARMIL2/APBB1/ADAMTS13 as Immune-Related Hub Genes Governing Radiotherapy Response and Prognosis in Pancreatic Cancer

2025-06-18

Abstract excerpt

Pancreatic cancer (PC) remains a therapeutic challenge due to intrinsic radioresistance, underscoring the urgent need for predictive biomarkers to stratify patients for personalized radiotherapy. Here, we integrated transcriptomic data from the Gene Expression Omnibus (GEO) database (4 radioresistant [RR] and 11 radiosensitive [RS] patients) and 178 pancreatic adenocarcinoma (PAAD) samples from TCGA to identify hu...

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Literature Corpus work
b0a82006-47c9-516e-b2e3-3b892423980b
DOI
10.22541/au.175024084.48270354/v1
Open publication

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Integrative Multi-omics Profiling Reveals CARMIL2/APBB1/ADAMTS13 as Immune-Related Hub Genes Governing Radiotherapy Response and Prognosis in Pancreatic CancerDOI 10.22541/au.175024084.48270354/v1
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