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Development and validation of an MBD3/UHRF1 methylation-regulator-based prognostic model for pancreatic cancer survival

1 Jun 2025

Abstract excerpt

Background: DNA methylation plays a crucial role in the onset and progression of cancer. However, the complex technology and high costs required for methylation detection limit its clinical application. DNA methylation regulators are essential for maintaining the precision and stability of gene methylation, and their aberrant expression can lead to abnormal methylation levels. Whereas the role of combinatorial...

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PMID: 40687248
DOI: 10.21037/tcr-24-1887

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